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NS4B and NS5 mutations expand the temperature range permissive for the replication of dual-host affiliated insect-specific flaviviruses in mosquito cells

Crossref DOI link: https://doi.org/10.1007/s00705-026-06584-7

Published Online: 2026-02-26

Published Print: 2026-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Kobayashi, Hiroko https://orcid.org/0000-0003-3348-733X
Tabata, Koshiro https://orcid.org/0000-0002-0227-2515
Sasaki, Michihito https://orcid.org/0000-0003-1607-2175
Hall, William W

Sawa, Hirofumi https://orcid.org/0000-0003-2569-2755
Orba, Yasuko https://orcid.org/0000-0001-9910-3912
Funding

Funding for this research was provided by:

Japan Society for the Promotion of Science (JP22KJ0133)

Japan Society for the Promotion of Science (JP23H03141)

Moonshot Research and Development Program (JPMJMS2025)

Japan Agency for Medical Research and Development (JP23fk0108637)

Japan Agency for Medical Research and Development (JP24wm0325073)

Japan Agency for Medical Research and Development (JP223fa627005)
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Text and Data Mining valid from 2026-02-26

Version of Record valid from 2026-02-26
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Article History

Received: 20 August 2025

Accepted: 31 January 2026

First Online: 26 February 2026

Declarations

:

: Not applicable.

: Not applicable.

: We declare no competing interests.

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