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Article History

Received: 13 May 2020

Accepted: 15 October 2020

First Online: 27 October 2020

Compliance with ethical standards

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: Dr. Govindarajan holds a post-doctoral fellowship from the Fund for Scientific Research – Flanders (FWO). The research was supported by grants from the Group-ID Multidisciplinary Platform (MRP) of Ghent University (Dr. Elewaut) and Fund for Scientific Research – Flanders (Dr. Elewaut). Dr. Rajasekahran holds a post-doctoral fellowship from the Fund for Scientific Research – Flanders (FWO). The authors would like to report research grants and non-financial support (i.e., cement materials free of charge) from Septodont, France. Outside of the submitted work, Dr. Martens and Dr. Rajasekharan report personal fees (honoraria/lecture fees/educational courses). In addition, Dr. Martens would like to report research grants from Septodont, France, negotiated with the Ghent University. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Ethical approval was obtained from the Ethical Committee of University Hospital, Ghent, Belgium, according to laws of ICH Good Clinical Practice (GE11-LM-go-2006/57).

: Informed consent was obtained from all individual participants included in the study.