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Authors
Pelá, Vinicius Taioqui
Gironda, Carlos Condarco
Taira, Even Akemi
Brito, Leonardo
Pieretti, Joana Claudio
Seabra, Amedea Barozzi
Cardoso, Cristiane de Almeida Baldini
Rodrigues, Marcela Charantola
Henrique-Silva, Flavio
Buzalaf, Marília Afonso Rabelo
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Funding
Funding for this research was provided by:
Fundação de Amparo à Pesquisa do Estado de São Paulo (Proc. 2017/04857-4, 2018/12041-7, 2019/26070-1, 2022/00321-0, 2022/13268-0 and 2020/03646-2)
Fundação de Amparo à Pesquisa do Estado de São Paulo (Proc. 2017/04857-4, 2018/12041-7, 2019/26070-1, 2022/00321-0, 2022/13268-0 and 2020/03646-2)
Fundação de Amparo à Pesquisa do Estado de São Paulo (Proc. 2017/04857-4, 2018/12041-7, 2019/26070-1, 2022/00321-0, 2022/13268-0 and 2020/03646-2)
Fundação de Amparo à Pesquisa do Estado de São Paulo (Proc. 2017/04857-4, 2018/12041-7, 2019/26070-1, 2022/00321-0, 2022/13268-0 and 2020/03646-2)
Fundação de Amparo à Pesquisa do Estado de São Paulo (Proc. 2017/04857-4, 2018/12041-7, 2019/26070-1, 2022/00321-0, 2022/13268-0 and 2020/03646-2)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (001)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (001)
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Article History
Received: 16 May 2023
Accepted: 15 July 2023
First Online: 22 July 2023
Declaration
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: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This work was approved by the Research Ethics Committee of Bauru School of Dentistry, University of São Paulo, SP, Brazil (CAAE:14973519.0.0000.5417).
: Informed consent was obtained from all individual participants included in the study. For Study 1, the protocol was performed in three experimental phases, including 15 volunteers. As for study 2, the protocol was performed in four experimental phases, including 16 volunteers. In both studies, the protocol was crossover and double-blind. Also, each phase consisted of 5 consecutive days, with a washout of 10 days. All volunteers took part in the study, after signing an informed consent document.
: The authors declare that they have no conflict of interest.
