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Article History

Received: 12 July 2019

Revised: 25 September 2019

Accepted: 17 October 2019

First Online: 28 January 2020

Compliance with ethical standards

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: All authors have access to the primary data and agree the journal can review data if requested. FZ and FL are employees of Janssen, who sponsored this research. SL is an employee of Adelphi Real World, who received funding from Janssen for this research. Other authors do not have a financial relationship with Janssen. A further and complete list of financial and non-financial disclosures for all authors follows: ES participated as Advisory board member, speaker or received grant support from AbbVie, Amgen, Bristol-Myers Squibb, GSK, Genzyme, Janssen, Lilly, Novartis, Pfizer, Roche, Sandoz, Sanofi, and UCB; IAP participated as Advisory board member from Novartis, Pfizer, and Janssen, and speaker to Janssen, Abbvie, Lilly, Roche, Pfizer, and Novartis; JMC received consulting fees and/or participated in Speakers’ Bureau for Pfizer, Merck Sharp and Dohme, Sanofi–Aventis, Genzyme, Novartis, Bristol-Myers Squibb, Roche, Boehringer-Ingelheim, Schering–Plough, Abbott, UCB, Eli Lilly, and Gilead; VFA received research funds from Abbvie, GSK, Janssen, Pfizer, BMS, Lilly, Boehringer-Ingelheim, Genentech, and UCB, participated as Advisory board member from Sandoz, Novartis, Lilly, Pfizer, Boehringer-Ingelheim, and Janssen, and speaker to Boehringer-Ingelheim, Janssen, Abbvie, Lilly, Celltrion, Pfizer, and Novartis; GG has no further conflicts of interest to disclose; WBM participated as speaker from Bristol-Myers Squibb, Janssen, Lilly, Novartis, and Pfizer; JCC participated as speaker from Abbvie, UCB, Jannsen, Pfzier, Novartis, Roche, and Celgene, and as Advisory board member from UCB, Jannsen, and Novartis; DVM participated as Advisory board member, speaker, or received grant support from Abbvie, Roche, UCB, and Pfizer; DRG participated as Advisory board member from Janssen and Lilly, and speaker from AbbVie, Amgen, Bristol-Myers Squibb, Janssen, Pfizer, and Roche; SL is an employee of Adelphi Real World and has no further conflicts of interest to disclose; FZ and FL are employees of Janssen and have no further conflicts of interest to disclose.

: All participating patients provided informed consent for use of their anonymized and aggregated data for research and publication in scientific journals. Data collection was performed such that patients and physicians could not be identified directly, and all data were aggregated and de-identified before receipt. Data collection was performed in accordance with the European Pharmaceutical Marketing Research Association guidelines; ethics committee approval was thus not required. Each survey was performed in full accordance with relevant legislation at the time of data collection, including the US Health Insurance Portability and Accountability Act 1996 [] and Health Information Technology for Economic and Clinical Health Act legislation [].