Sumner, Emma J.
Almeida, Beverley
Palman, Jason
Bale, Peter
Heard, Clare
Holzinger, Dirk
Roth, Johannes
Foell, Dirk
Robinson, Emily
Ursu, Simona
Wallace, Chris
Gilmour, Kimberly
Wedderburn, Lucy R.
Ralph, Elizabeth
Funding for this research was provided by:
UK National Institute for Health Research Biomedical Research Centre
Sparks (17ICH02)
UK Research and Innovation Medical Research Council (MR/R013926/1, MC_UU_00002/4)
Versus Arthritis (22084, 21593)
Great Ormond Street Hospital Charity
Wellcome Trust (WT107881)
Article History
Received: 23 February 2022
Revised: 1 April 2022
Accepted: 3 April 2022
First Online: 29 April 2022
Declarations
:
: The study was conducted in accordance with the ethical standards laid down in the Declaration of Helsinki. The overall analysis was performed as a clinical audit and had local approval from Great Ormond Street Hospital Audit Committee. Some patient data from the CHARMS study were also included: CHARMS had full ethical approval from London Bloomsbury Research Ethics Committee approved the study (MREC 95RU04) and all participating families provided written informed consent prior to enrolment. This manuscript does not contain personal identifiable data from any individual.
: Not applicable.
: The UKRI-funded CLUSTER consortium (PI LRW) has partnerships with industrial partners currently GSK, AbbVie, UCB, Sobi and Pfizer, and CW has received funding from GSK and Merck Sharp Dohme. None of these were directly involved in the data, analysis or interpretation of this work. The authors have full control of all primary data and that they agree to allow the journal to review their data if requested.