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Authors
Rogowska, Jagoda https://orcid.org/0009-0004-5995-5802
Kubicka, Jagoda https://orcid.org/0009-0004-6464-4777
Grabowska, Martyna https://orcid.org/0009-0002-4030-8272
Mirocha, Grzegorz https://orcid.org/0009-0006-4621-6247
Roszkiewicz, Justyna https://orcid.org/0000-0003-1487-7156
Smolewska, Elżbieta https://orcid.org/0000-0002-8421-0448
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Article History
Received: 2 February 2025
Revised: 20 March 2025
Accepted: 23 March 2025
First Online: 27 March 2025
Declarations
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: All procedures performed in studies involving human participants were performed in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Ethical approval was taken from the Medical University of Lodz Ethics Committee (approval no: RNN/08/25/KE, 14.01.2025).All parents or legal guardians of the participants provided written informed consent for their children's participation in the study.
: Informed consent was obtained from all subjects before enrolment.
: Additional informed consent was obtained from all individual participants for whom identifying information is included in this article.
: The authors have no relevant financial or non-financial interests to disclose.
: This study has been previously presented at the conference.
: This paper has been prepared by the authors without the involvement of editing agencies. No AI technologies or editing software were utilized in the creation of this work.
: The figures and tables were created by authors using GIMP, Canva, and Microsoft Word. These tools provided essential features for designing and editing the graphics.
: We conducted a systematic search using Medline/PubMed, Scopus, and DOAJ from 2010 to 2025. Keywords used included: "MAS," "systemic juvenile idiopathic arthritis," "macrophage activation syndrome," and "predictive markers." Boolean operators combined search terms: ("MAS" AND "sJIA") OR ("macrophage activation syndrome" AND "juvenile idiopathic arthritis"). Articles were filtered for English language and relevance to diagnosis and management. We screened 93 articles and included 19 relevant studies.
