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Authors
Parikh, Ankit https://orcid.org/0009-0001-8014-5781
Lewis, Gwyn https://orcid.org/0000-0001-9324-0940
GholamHosseini, Hamid https://orcid.org/0000-0002-0135-2687
Ng, Kristine Pek Ling https://orcid.org/0009-0006-6225-2715
Kluger, Michal https://orcid.org/0000-0003-0842-7298
Almesfer, Faisal https://orcid.org/0000-0002-5924-0135
Chang, Wee Leong https://orcid.org/0000-0002-9675-9737
Rice, David https://orcid.org/0000-0002-3327-8776
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Funding
Funding for this research was provided by:
Exsurgo Ltd
Auckland University of Technology
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Article History
Received: 25 November 2025
Revised: 11 March 2026
Accepted: 12 March 2026
First Online: 23 March 2026
Declarations
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: The New Zealand Health and Disability Ethics Committee (HDEC) approved this study on 8 December 2023 (reference number 18139). The study was registered on the Australian New Zealand Clinical Trials Registry (ANZCTR) on 14 May 2024 (registration ACTRN12624000620527). The study was conducted according to the procedures specified in the study protocol and under the principles of the Declaration of Helsinki, CHMP GCP Guidelines on Good Clinical Practice E6(R2), and National Statement on Ethical Conduct in Research Involving Humans.
: All participants provided written informed consent.
: Authors Ankit Parikh and Faisal Almesfer were employed by the company Exsurgo Ltd. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.
