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Article History

Received: 3 April 2022

Accepted: 11 June 2022

First Online: 25 June 2022

Declarations

:

: The research protocol was approved in each site by the local ethics committee. Before enrollment, patients signed informed consent to participate in the study.

: Isabelle Lecomte and Nora Blanchard are employees of Bioprojet. Tommaso Sacco is a consultant of Bioprojet and has received support for meeting attendance from Bioprojet. Valerio Brunetti has received support for meeting attendance from Bioprojet. Luigi Ferini-Strambi has received honoraria for lectures, presentations, or advisory board from Bioprojet, Jazz, Lundbeck, Sanofi, Italfarmaco, Valeas, and Angelini. Raffaele Ferri has received honoraria for lectures, presentations, or advisory board from Bioprojet and Elsevier. Rocco Liguori has received honoraria for lectures, presentations, or advisory board from Galen Symposion s.r.o., Planning Congressi s.r.l., P.T.S. s.r.l., LT3 s.r.l., PREX s.r.l., ARGENX BV, Alexion Pharma s.r.l., Amicus Therapeutics, and UCB. Lino Nobili has received honoraria for lectures from Bioprojet and consulting fees from Fidia Pharma, Eisai, and Roche. Fabio Pizza has received honoraria for presentation from Jazz and support for meeting attendance from Bioprojet. Giuseppe Plazzi has received honoraria for advisory board and consulting fees from Bioprojet, Jazz, Takeda, and Idorsia. Monica Puligheddu has received honoraria for educational events from Jazz and Livanova. Andrea Romigi has received honoraria for lectures, presentations, or advisory board from Bioprojet, Jazz, and Eisai. All other authors have no relevant conflict of interest to disclose related to the content of the current manuscript.