Document is current
Any future updates will be listed below
-
Authors
Appleton, Jason P. https://orcid.org/0000-0002-2604-4410
Woodhouse, Lisa J.
Beridze, Maia
Christensen, Hanne
Dineen, Rob A.
England, Timothy J.
Ranta, Anna
Robinson, Thompson G.
Sprigg, Nikola
Bath, Philip M. https://orcid.org/0000-0003-2734-5132
,
-
Funding
Funding for this research was provided by:
British Heart Foundation (PG/08/083/25779)
Health Technology Assessment Programme (10/104/24)
Nottingham University Hospitals NHS Trust (Research)
Nottingham University Hospitals NHS Trust (Innovation award)
- License Information
-
More Information
Article History
Received: 17 August 2025
Accepted: 20 November 2025
First Online: 24 January 2026
Declarations
:
: The trial was approved by the East Midlands UK research ethics committee (08/H1102/112), registered (ISRCTN47823388), adopted by the National Institute of Health Research (NIHR) Clinical Research Network, and sponsored by the University of Nottingham, UK. National competent authorities gave approvals for the study in each participating country. The trial was overseen by a trial steering committee and an international advisory committee, comprising each national coordinator.
: JPA is supported, in part, by a Nottingham University Hospitals Research & Innovation award; PMB is Stroke Association Professor of Stroke Medicine and an Emeritus NIHR Senior Investigator; TGR is an NIHR Senior Investigator. All other authors have no competing interest to declare.
