Funding for this research was provided by:
West China Hospital of Sichuan University under the project entitled Clinical application of topological perceptual networks in monitoring the therapeutic efficacy of anti-Aβ monoclonal antibodies (Grant No. HX-H2511528)
Article History
Received: 27 January 2026
Accepted: 31 March 2026
First Online: 18 April 2026
Declarations
:
: The authors declare that they have no conflicts of interest.
: All data were de-identified prior to publication.
: This report describes clinical care and ancillary investigations in a single family. In accordance with the West China Hospital of Sichuan University’s policy, formal ethical approval was waived for anonymized case reports.
: Written informed consent was obtained from the proband’s legally authorized representative and from the participating family member for clinical evaluation and genetic testing.
: Written informed consent for publication of anonymized clinical information, imaging, and genetic findings (including Figs. and and Supplementary materials) was obtained from the participating family member.