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Authors
Massart, Nicolas https://orcid.org/0000-0001-5828-0197
Ortuno, Sofia
Vidal, Charles
Henri, Samuel
Rozé, Hadrien
Bouglé, Adrien
Manicone, Francesca
Bidar, Frank
Assouline, Benjamin
Masi, Paul
Hraiech, Sami
Nesseler, Nicolas
de Montmollin, Etienne
Luyt, Charles-Edouard
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Article History
Received: 18 October 2024
Accepted: 3 February 2025
First Online: 8 February 2025
Declarations
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: In accordance with the declaration of Helsinki, the protocol was submitted and then approved by the ethics committee of the Société de Réanimation de Langue Française (registration no. CE-SRLF-22–074) and the database is registered by the Commission Nationale de l’Informatique et des Libertés (CNIL, registration no 2228484v 0).
: In accordance with current French law, informed written consent for demographic, physiologic and hospital-outcome data analyses was waived because this observational study did not modify existing diagnostic or therapeutic strategies. Nonetheless, patients and/or relatives were informed about the anonymous data collection and told that they could decline inclusion.
: The authors declare no competing interests.
: Groupe Hospitalier Pitié-Salpêtrière, Paris, France: Juliette Chommeloux, Guillaume Hékimian, Alain Combes, Nima Djavidi, Aymeric Lancelot, Pauline Dureau, Guillaume Lebreton. CH de Saint-Brieuc, France: Pierre Fillâtre. Centre Hospitalier Universitaire de La Réunion, Saint Denis, France: Laura Rivoire, Nicolas Allou, Radj Cally. Hôpital Bichat-Claude Bernard, Paris, France: Hermann Do Rego, Mariem Dlela, Marc Doman. Centre Hospitalier universitaire de Rennes: Christophe Camus, Erwan Flecher, Alexandre Mansour. Hôpital Louis Pradel, Lyon, France: Jean-Luc Fellahi, Matteo Pozzi, Matthias Jacquet-Lagreze. Hôpitaux Universitaires de Genève, Genève, Switzerland: Raphaël Giraud, Karim Bendjelid. Hôpital Henri Mondor, Créteil, France: Keyvan Razazi, Armand Mekontso-Dessap. Hôpital universitaire de Lille, Lille, France: Anahita Rouzé, Saad Nseir, Thibault Duburcq. Hôpital Nord, Marseille, France: Christophe Guervilly, Jean-Marie Forel. Hôpital Haut Leveque, Pessac, France: Eline Bonnardel. Hôpital Universitaire de Bruxelles, Brussels, Belgium: Fabio S Taccone.
: Among ECMO patients with bloodstream infection, incriminated microorganisms were dominated by Enterococcus sp., Enterobacterales and coagulase negative Staphylococci. Mortality was high (50%).
: Base on observed microbiology, high appropriateness would only be obtained with piperacilline/tazobactam or carbapenems in association with vancomycin. Future trial evaluating empirical therapy in this setting are needed.
