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Authors
Yamaguchi, Ryo
Yamamoto, Takehito
Harada, Sohei
Shibuya, Mayu
Mizoguchi, Miyuki
Higurashi, Yoshimi
Miyata, Yuki
Ogiue, Naoki
Tsutsumi, Takeya
Takada, Tappei
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Funding
Funding for this research was provided by:
The University of Tokyo
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Article History
Received: 18 November 2025
Accepted: 11 March 2026
First Online: 20 March 2026
Declarations
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: This study was approved by the Research Ethics Committee of the Faculty of Medicine of the University of Tokyo (approval No. 2023138NI).
: During the preparation of this work the authors used ChatGPT 5 (OpenAI) and Gemini 2.5 Pro (Google) in order to polish the English language and improve readability. After using these tools, the authors reviewed and edited the content as needed and take full responsibility for the content of the published article.
: The requirement for written informed consent was waived by the ethics committee due to the retrospective nature of the study.
: Not applicable. The manuscript does not contain any individual person’s data in any form.
: SH reports speaker payments from MSD, Shionogi, Pfizer and consulting fees from Shionogi, Pfizer, Denka outside the submitted work. All other authors declare no conflict of interest.
