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Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial

Crossref DOI link: https://doi.org/10.1007/s10103-025-04703-5

Published Online: 2025-10-24

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sitohang, Irma Bernadette S. https://orcid.org/0000-0002-2753-6716
Arimuko, Abraham

Norawati, Lilik https://orcid.org/0009-0008-8578-5834
Maria, Rita

Yulyana, Cyntia

Nugraha, Randy Satria

Amanda, Vashty

Indrafatina, Arsy

Amalia, Inasa
Funding

Funding for this research was provided by:

PT. Taisho Pharmaceutical Indonesia, Tbk (EzerraTM).
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Text and Data Mining valid from 2025-10-24

Version of Record valid from 2025-10-24
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Article History

Received: 1 July 2025

Accepted: 6 October 2025

First Online: 24 October 2025

Declarations

:

: This research received ethical approval from the Ethics Committee of the Faculty of Medicine, Universitas Indonesia (Ethical approval number: KET-1130/UN2.F1/ETIK/PPM.00.02/2021.

: This trial was registered at ClinicalTrials.gov (registration number: NCT05186246).

: This study was conducted in accordance with the Declaration of Helsinki. Written informed consent was obtained from all participants.

: The authors declare no competing interests.

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