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Article History

Received: 26 May 2023

Accepted: 19 October 2023

First Online: 15 November 2023

Declarations

:

: AC declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events or participation on a data safety monitoring board or advisory board from BMS, MSD, Lilly, Ipsen, Novartis and Esteve. PJF declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events or participation on a data safety monitoring board or advisory board from Adacap, BMS, Lilly, MSD, Astellas and Astra Zeneca. ACB declares he has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing or educational events from Amgen, Astellas, Bayer, BMS, Eisai, Lilly, MSD, Merck, Novartis, Roche and Servier. AL declares he has received support for attending meetings and/or travel from Roche, Pfizer, Lilly and MSD. AFM declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing or educational events from Servier, Amgen, Pierre Fabre, Merck, Eisai, Roche, Lilly and Astra Zeneca. MD declares he has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events, attending meeting and/or travel from Lilly and BMS. RVT declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events, participation on a data safety monitoring board or advisory board, expert testimony, attending meeting and/or travel from Merck, BMS and Amgen. MGR declares she has received grants or contracts from Lilly, Amgen and Servier and payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events, attending meeting and/or travel from Servier, Lilly, Amgen and Merck. MMR declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events or participation on a data safety monitoring board or advisory board from BMS, MSD, Astellas y Astra Zeneca. PC declares she has received payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events or participation on a data safety monitoring board or advisory board, attending meeting and/or travel from BMS, Roche, Lilly, Eisai, Servier and Astra Zeneca. JG declares he has received research funding from Astellas, Astra Zeneca, BMS, Daiichi-Sankio, Lilly, Servier and payment or honoraria for lectures, presentations, speakers, bureaus, manuscript writing, educational events or participation on a data safety monitoring board or advisory board, attending meeting and/or travel from AAA, Amgen, Bayer, BMS, Eisai, Ipsen, Lilly, Merck, MSD, Novartis, Servier, Pierre-Fabre, Roche and Veracyte. The other authors declare that they have no conflict of interest regarding the scope of this article.

: All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions. Informed consent or a substitute for it was obtained from all patients before they were included in the study. Ethics committee Hospital General Universitario Morales Meseguer approved the study (C.P.AGAMENONC.I.EST:30/14, 26 November 2014). Informed consent was obtained from all patients before being included in the study. This work is original and has not been previously presented elsewhere.