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Authors
Yonezawa, Ryo
Meng, Lingxin
Hashimoto, Naoki
Igarashi, Ibuki
Kimura, Satoshi
Yasuda, Nina
Mitsuyama, Susumu
Kobayashi, Takanori
Yoshitake, Kazutoshi
Kinoshita, Shigeharu
Bailey-Kobayashi, Nahoko
Maeyama, Kaoru
Nagai, Kiyohito
Watabe, Shugo
Yoshida, Tetsuhiko
Asakawa, Shuichi
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Funding
Funding for this research was provided by:
The University of Tokyo
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Article History
Received: 31 December 2025
Accepted: 13 April 2026
First Online: 25 April 2026
Declarations
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: The authors declare that this manuscript complies with Springer’s Ethical Guidelines for Journal Publication.
: The authors declare the following potential competing interests: Financial support for this study was provided by a research donation from Mikimoto Pharmaceutical Co., Ltd. Additionally, funding was provided through a social cooperation program endowed by Toagosei Co., Ltd. Technical and experimental support was provided by K. Mikimoto & Co., Ltd. Naoki Hashimoto, Nahoko Bailey-Kobayashi, Kaoru Maeyama, Kiyohito Nagai and Tetsuhiko Yoshida are employees of these respective companies. However, the authors declare that this study constitutes fundamental basic research. The affiliated companies and funding sources did not compromise the scientific objectivity or integrity of the study design, data analysis, or data interpretation. The findings do not promote any specific commercial products and yield no direct commercial advantage to the affiliated companies. The authors declare no other competing interests.
