Wang, Fang https://orcid.org/0000-0002-1474-2297
Wei, Mingkun
Xu, Dingkang https://orcid.org/0000-0002-9153-773X
Wang, Zikuo
Yang, Jichao
Lou, Yongli
Hui, Lei
Yue, Shuangzhu
Liu, Yongsheng
Yang, Zhen
Zhang, Yuanfeng
Wei, Yitong
Gao, Yansheng
Wang, Qinglin
Zhao, Shengqi
Guo, Xiaolong
Wu, Jinsong
Wei, Qingjie
Jian, Yanpeng
Ji, Kangqi
Shan, Qiao
Liu, Jinyu
Jian, Li
You, Haojun
Yao, Qinghe
Yao, Jiali
Feng, Shubin
Feng, Qiang
Fang, Dandong
An, Yuan https://orcid.org/0000-0002-6347-7653
Du, Yan
Zhang, Mingchu
Zhang, Kaiyuan https://orcid.org/0009-0008-5934-1236
Fang, Junhao
Feng, Mengzhao https://orcid.org/0000-0002-0933-1899
Li, Mengyuan
Song, Dengpan https://orcid.org/0000-0001-5240-7601
Wang, Bangqing
Yin, Kai
Hu, Yan
Zuo, Yuchao
Yu, Bin
Wang, Weiguang
Yuan, Ruixia
Turgut, Ali Çağlar
Eraslan, Cenk
Zhang, Jun
Lazareff, Jorge A.
Guo, Fuyou https://orcid.org/0000-0001-9332-8272
Funding for this research was provided by:
Key scientific and technological projects in Henan Province (242102311220)
National Natural Science Foundation of China (82503692)
Key project of international science and technology cooperation, Science and Technology Department of Henan Province (241111520600)
Project of Clinical Research for Doctor of Henan Province (HNCRD202424)
Henan Province science and technology research project (232102310127)
Article History
Received: 2 July 2025
Revised: 1 November 2025
Accepted: 16 November 2025
First Online: 9 December 2025
Declarations
:
: Ethics approval was obtained from the Ethics Committee of all the 14 participating centers. The Ethics Committee of the The First Affiliated Hospital of Zhengzhou University(2023-KY-1394-002), The Ethics Committee of the Henan Provincial People’s Hospital(2024-087), The Ethics Committee of the Zhengzhou Central Hospital(202467), The Ethics Committee of the First Affiliated Hospital of Xinxiang Medical University(2024-07), The Ethics Committee of the First People’s Hospital of Shangqiu City(KS2024023), The Ethics Committee of the Nanyang Center Hospital(KYLL-12061424), The Ethics Committee of the Zhumadian Central Hospital(2024-03-020K01), The Ethics Committee of the First Affiliated Hospital of Henan University of Science and Technology University(2024 − 1165), The Ethics Committee of the Xuchang Central Hospital(2024-08-003), The Ethics Committee of the Third Affiliated Hospital of Zhengzhou University(2024-202-01), The Ethics Committee of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine (2024HL-382-01), The Ethics Committee of the Luoyang Central Hospital(2024-013-01), The Ethics Committee of the Children’s Hospital Affiliated to Zhengzhou University(2024-053), and The Ethics Committee of the Sanmenxia Central Hospital(2024-02). Patients and their families informed and agreed to this study.
: All authors of the manuscript agreed to its publication.
: The authors declare no competing interests.