Huang, Tao
Fan, Zhimin
Wang, Yongsheng
Yan, Xi
Yang, Hongjian
Wang, Shu
Pang, Da
Li, Huiping
Wang, Haibo
Geng, Cuizhi
Huang, Liang
Sun, Yaqing
Wang, Bei
Sun, GuofangÂ
Siddiqui, Asna
Restuccia, Eleonora
Shao, Zhimin
Funding for this research was provided by:
F. Hoffmann-La Roche
Article History
Received: 25 July 2025
Accepted: 27 November 2025
First Online: 7 May 2026
Declarations
:
: Tao Huang, Zhimin Fan, Yongsheng Wang, Xi Yan, Hongjian Yang, Shu Wang, Da Pang, Huping Li, Haibo Wang, Cuizhi Geng, Liang Huang, and Zhimin Shao report research funding (investigator fees for this study paid to their institution) from F. Hoffmann-La Roche Ltd. Yaqing Sun is an employee of Roche (China) Holding Co. Ltd. Guofang Sun is an employee of Roche (China) Holding Co. Ltd and holds stocks/shares in F. Hoffmann-La Roche Ltd. Bei Wang is an employee of Genentech, Inc. and holds stocks/shares in F. Hoffmann-La Roche Ltd. Asna Siddiqui is an employee of Roche Products Limited and holds stocks/shares in F. Hoffmann-La Roche Ltd. Eleonora Restuccia is an employee of and holds stocks/shares in F. Hoffmann-La Roche Ltd. Non-financial interests: All authors received research funding in the form of third-party medical writing assistance for this manuscript from F. Hoffmann-La Roche Ltd.
: The study was performed in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. Approval for the study protocol and all accompanying material provided to patients was obtained from independent ethics committees at participating institutions.
: Informed consent was obtained from all individual participants involved in the study.