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Authors
Okada, Masafumi https://orcid.org/0000-0002-7715-5292
Matsumoto, Shigemi
Maehara, Yuriko
Kanayama, Tomoko
Lambrelli, Dimitra
Koga, Tadashi
Muto, Manabu
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Funding
Funding for this research was provided by:
Japan Agency for Medical Research and Development (JP25zf0227104)
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Article History
Received: 7 November 2025
Accepted: 8 March 2026
First Online: 24 April 2026
Change Date: 12 July 2026
Change Type: Update
Change Details: The Supplementary file was missing from this article and has now been uploaded.
Declarations
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: MO, YM, and TK are employees of PRiME-R, which serves as the administrative office for the J-CONNECT registry under a contract with Kyoto University. DL is an employee of PPD Evidera. TKo is an employee of Clinical Study Support Inc.
: This analysis used only a secondary aggregated summary table of the J-CONNECT database. Therefore, no additional individual-level informed consent was obtained for conducting this analysis.
: Not applicable.
: Not applicable.
