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Authors
Nguyen, Phuong Thanh
Nakaoka, Hirofumi https://orcid.org/0000-0002-8454-1159
Mitsunaga, Shigeki
Aoyama, Hiromichi
Kitamura, Hiroshi
Saigo, Kenichi
Inoue, Ituro
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Funding
Funding for this research was provided by:
JSPS KAKENHI (JP16K10445)
AMED (24ek0510040h0002)
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Article History
Received: 22 September 2025
Accepted: 4 May 2026
First Online: 2 June 2026
Declarations
Conflict of interest: I.I and S.M are cofounders of iSan Bio Inc., a company whose focus lies outside the scope of this study and has no influence on its results or conclusions. All the authors have declared no competing interest.
Ethical approval: All procedures performed in this study was approved by the institutional ethical boards of National Hospital Organization Chiba-East Hospital (Approved ID: 41) and the National Institute of Genetics (Approved ID: 28 − 7). This study was in accordance with the 1964 Helsinki declaration including its later amendments, and with the Declaration of Istanbul. This article does not contain any studies with animals performed by any of the authors.
Informed consent: Informed consent was obtained from all individual participants included in the study.
