Gebert, Pimrapat https://orcid.org/0000-0002-5946-7137
Hage, Anna Maria https://orcid.org/0000-0003-1612-8052
Fischer, Felix https://orcid.org/0000-0002-9693-6676
Klapproth, Christoph Paul https://orcid.org/0000-0001-6057-5920
Grittner, Ulrike https://orcid.org/0000-0003-2595-0224
Karsten, Maria Margarete https://orcid.org/0000-0001-7587-7550
Funding for this research was provided by:
Charité - Universitätsmedizin Berlin
Article History
Received: 18 February 2025
Accepted: 14 July 2025
First Online: 21 August 2025
Declarations
:
: The study was conducted in accordance with the Helsinki Declaration and ICH guidelines for good clinical practice. The PRO B study was approved by the institutional review board of Charité– Universitätsmedizin Berlin (application number: EA1/318/20) and was individually adapted for all the participating study sites. Participation was voluntary, and written informed consent was mandatory prior to enrollment. It was obtained by the treating physician during routine clinical visits.
: The authors declare that they have no competing interests.