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Article History

Received: 17 May 2025

Accepted: 24 August 2025

First Online: 25 October 2025

Declarations

:

: The authors declare that they have no competing interests.

: All bioinformatics data incorporated in this study were sourced from publicly accessible databases. There is no moral, legal, or relevant conflicts of interest. The patients involved in these databases have obtained ethical approval. The experimental data do not involve the leakage of patients’ personal information and do not harm the patients’ interests. This study received approval from the Biomedical Research Ethics Review Committee of Xuzhou Central Hospital (Version: V1.0; Approval Date: 2024-01-01; Ethics Number: XZXY-LK-20240926-0150). This study complied with the Declaration of Helsinki and all applicable ethical guidelines.

: Informed consent was obtained from all subjects involved in the study.

: Not applicable.