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Authors
Daenen, Katrijn https://orcid.org/0009-0003-5664-5393
Rizopoulos, Dimitris
Dalm, Virgil A. S. H.
Huijben, Jilske A.
Stoof, Sara C. M.
Nagtzaam, Nicole M. A.
Dik, Willem A.
Swagemakers, Sigrid M. A.
van der Spek, Peter J.
Tong-Minh, Kirby
Mersha, Daniel G. Aynekulu
Khyali, Jessica
Juffermans, Nicole P.
Gommers, Diederik
van Gorp, Eric C. M.
Bos, Lieuwe D. J.
Endeman, Henrik
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Clinical Trials BETA
Clinical trials referenced in this document:
nct05403359 at ClinicalTrials.govDocuments that mention this clinical trial
Increasing inflammatory biomarkers are associated with mortality in critically ill COVID-19 patients despite anti-inflammatory treatment
https://doi.org/10.1007/s10238-025-01904-8
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Funding
Funding for this research was provided by:
ZonMw (0430102110010)
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Article History
Received: 11 August 2025
Accepted: 13 September 2025
First Online: 11 November 2025
Declarations
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: The authors declare that they have no competing interests.
: The study was approved by the local Medical Ethics Review Committee under protocol number MEC-2017–417 and conducted in accordance with the principles of the Declaration of Helsinki. Due to the urgency of conducting research in patients with COVID-19, an exemption for consent was approved by the Medical Research Ethics Committee at the Erasmus University Medical center. An opt-out informed consent procedure (MEC-2022–0297) was used, and patients who expressed objections to participation were excluded from the study. No other exclusion criteria were applied.
: Not applicable.
