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PD-L2 deficiency in Alveolar macrophages drives fibrosis, apoptosis, and ferroptosis via M1 polarization in connective tissue disease-associated interstitial lung disease

Crossref DOI link: https://doi.org/10.1007/s10238-026-02115-5

Published Online: 2026-03-13

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Lu, Junhui

Feng, Xiuyuan

Chang, Xin

Cheng, Wei

Pan, Pengfei

Wu, Jian
Funding

Funding for this research was provided by:

Wu Jian scientific research award fund card project (N/A)
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Text and Data Mining valid from 2026-03-13

Version of Record valid from 2026-03-24
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Article History

Received: 17 November 2025

Accepted: 18 February 2026

First Online: 13 March 2026

Declarations

:

: All authors approved the final manuscript and have consented to publication.

: The authors declare no competing interests.

: The study involving humans was approved by the Institutional Ethics Committee (Approval No. HEYLL2024059). All animal procedures performed in this study were reviewed and approved by the Soochow University Animal Care and Use Committee (Approval No. GPTAP002).

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