Choquet, Karine http://orcid.org/0000-0001-9274-8320
Vappou, Jonathan
Cabras, Paolo
Ishak, Ounay
Gangi, Afshin
Breton, Elodie
Funding for this research was provided by:
Fonds Unique Interministériel
Institute of Image Guided Surgery (ANR-10-IAHU-02)
LabCom TechnoFUS (ANR-21-LCV3-0007-01)
LABEX-CAMI (ANR-11-LABX-004)
Article History
Received: 16 September 2022
Revised: 6 January 2023
Accepted: 10 January 2023
First Online: 1 February 2023
Declarations
:
: The authors declare that they have no conflict of interest.
: The in vivo experiment was led following the 3R principle for more humane research, and in following local legal ethics regulation (registered project APAFIS #14092-2018031513247711v1). The animal was maintained under gaseous anaesthesia during imaging (1.8% isoflurane), with appropriate pain management (Propofol 1mg/kg) during HIFU. At the end of the experiment, the animal was euthanized through anaesthetics overdose (10 min, 5% isoflurane) coupled to IV injection of saturated KCl solution (0.5 mL/kg).