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Article History

Received: 9 July 2021

Accepted: 27 December 2021

First Online: 20 January 2022

Declarations

:

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

: Yukiko Mori received honoraria from Daiichi Sankyo and Nipponkayaku. Osamu Kikuchi declares that he has no conflict of interest. Takahiro Horimatsu declares that he has no conflict of interest. Hiroki Hara received grants from Astellas, AstraZeneca, Bayer, BeiGene, Boehringer Ingelheim, Chugai, Daiichi Sankyo, Dainippon Sumitomo, Eisai, Elevar Therapeutics, GSK, Incyte, Merck Biopharma, MSD, Ono, Pfizer, and Taiho, consulting fees from Boehringer Ingelheim, Daiichi Sankyo, Dainippon Sumitomo, Lilly, MSD, Ono, honoraria from Bayer, Bristol-Myers Squibb, Chugai, Daiichi Sankyo, Kyowa Hakko Kirin, Lilly, Merck Biopharma, MSD, Ono, Sanofi, Taiho, Takeda, and Yakult. Shuichi Hironaka received research funding and honoraria from Taiho. Takashi Kojima received grants from MSD, Ono, Bristol-Myers Squibb, Astellas Amgen BioPharma, Taiho Pharmaceutical, Chugai, and Shionogi and received honoraria from Ono, Bristol-Myers Squibb, MSD, Astellas Pharma, Merk, and Oncolys BioPharma. Ken Kato received research funding from Ono, participation on a Data Safety Monitoring Board or Advisory Board for Bristol-Myers Squibb, MSD, and Roche, and was a leadership or fiduciary role on other boards, society, join committees, or advocacy groups for BMS, MSD, and BeiGene. Takahiro Tsushima declares that he has no conflict of interest. Ryu Ishihara declares that he has no conflict of interest. Kumi Mukai declares that she has no conflict of interest. Ryuji Uozumi received consulting fees from Eisai, Sawai Pharmaceutical, and CAC croit. Harue Tada declares that she has no conflict of interest. Hiroi Kasai declares that she has no conflict of interest. Atsushi Kawaguchi declares that he has no conflict of interest. Manabu Muto received funding support from Taiho.

: Informed consent was obtained from all individual participants included in the study.