Benjaminsen, Camilla R. https://orcid.org/0009-0000-6104-1314
Jørgensen, Rasmus M. https://orcid.org/0000-0001-9910-8924
Pedersen, Malthe J. https://orcid.org/0000-0003-1510-3179
Clausen, Loa https://orcid.org/0000-0002-4559-8347
Østergaard, Jane N. https://orcid.org/0000-0002-0627-1237
Bruun, Jens M. https://orcid.org/0000-0001-9937-5467
Funding for this research was provided by:
Aarhus University Hospital
Article History
Received: 25 November 2025
Accepted: 18 March 2026
First Online: 16 April 2026
Declarations
:
: This study was conducted following the principles outlined in the Declaration of Helsinki and received approval from the Danish Data Protection Agency and from the Central Jutland Regional Committee on Health Research Ethics (reference no. 1-45-70-27-20), with a supplementary application approved on September 5, 2023. The project was registered at ClinicalTrials.gov (NCT06555380) and in the local directory at Aarhus University (record no. 2022-0367531).
: The Central Jutland Regional Committee on Health Research Ethics waived the requirement for informed consent. Since the study was register-based, with no direct contact with the included families, the authors ensured that no data were reported at an individual level.
: Not applicable.
: Rasmus M Jørgensen, Jane N Østergaard, and Jens M Bruun are employed at Steno Diabetes Center Aarhus, a public hospital and research institution in the Central Denmark Region, partly funded by an unrestricted grant from the Novo Nordisk Foundation. Camilla R Benjaminsen, Loa Clausen, and Malthe J Pedersen have no conflicts of interest to disclose. The Novo Nordisk Foundation had no role in the study design or conduct.