Lanyon, Christopher W https://orcid.org/0000-0001-6627-9268
Rodero, Cristobal https://orcid.org/0000-0001-7921-7840
Qayyum, Abdul https://orcid.org/0000-0003-3102-1595
Baptiste, Tiffany MG https://orcid.org/0000-0003-3157-3568
Niederer, Steven A https://orcid.org/0000-0002-4612-6982
Wilkinson, Richard D https://orcid.org/0000-0001-7729-7023
Funding for this research was provided by:
Engineering and Physical Sciences Research Council ((EP/X012603/1))
Article History
Received: 10 April 2025
Accepted: 14 October 2025
First Online: 17 November 2025
Declarations
:
: The authors have no relevant financial or non-financial interests to disclose.
: Both case studies in this paper include results that rely on personalised patient meshes generated using medical imaging. The data for these case studies were not explicitly generated as part of the research for this work, but the relevant ethics declarations are shown below.Electrophysiology Case Study:The imaging data were collected as part of a prospective study approved by the Health Research Authority of St Thomas' Hospital, London, UK (18/LO/1803). The study conformed with the Declaration of Helsinki (reference ID 15/LO/1803) and all participants provided written, informed consent.Atrial Mechanics Case Study:This study complied with the Declaration of Helsinki and the protocol was approved by the West Midlands Coventry and Warwick ethics committee and the London-Harrow ethics committee (clinical trial REC numbers 14/WM/1069 and 18/LO/0752) . The study was conducted in accordance with the local legislation and institutional requirements. Each patient provided written informed consent, and images were anonymised prior to analysis.