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A Novel Demography-Based Approach to Define Patient-Specific Outflow Boundary Conditions in CT-Based FFR Computations

Published Online: 2026-03-03

Authors

Lo, Ernest W. C.

Pugliese, Francesca

Menezes, Leon

Torii, Ryo https://orcid.org/0000-0001-9479-8719
Funding

Funding for this research was provided by:

EPSRC Centre for Doctoral Training in Medical Imaging (EP/L016478/1)
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Article History

Received: 26 September 2025

Accepted: 25 January 2026

First Online: 3 March 2026

Declarations

:

: There is no conflict of interests that the authors need to declare regarding this study.

: The PET data set used in this study was obtained in accordance with the recommendations of the South East Research Ethics Research Committee (Aylesford, Kent, UK). The study protocol involving CT and invasive FFR for the CTP cohort was approved by the East Central London Research Ethics Committee (10/H0721/79).

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