Sovilj, Dana
Kelemen, Cristina Daniela
Dvorakova, Sarka
Zobalova, Renata
Raabova, Helena
Kriska, Jan
Hermanova, Zuzana
Knotek, Tomas
Anderova, Miroslava
Klener, Pavel
Filimonenko, Vlada
Neuzil, Jiri
Andera, Ladislav https://orcid.org/0000-0003-3073-2280
Funding for this research was provided by:
Czech Science Foundation (GA19-08772S, GX21-04607X)
Institute of Biotechnology (86652036)
Ministry of Education, Youth and Sports of the Czech Republic (LM2023050)
Czech Academy of Sciences (L200392251)
Ministry of Health of the Czech Republic (NU21-03-00386)
Article History
Accepted: 29 October 2023
First Online: 24 November 2023
Declarations
:
: Jiri Neuzil is co-owner of MitoTax s.r.o., receives no compensation, and has no competing or financial interest. The other authors have no relevant financial or non-financial interests to disclose
: Subcutaneous xenotransplantations into NSG mice and follow-up surveillance were performed in accordance with the European Communities Council Directive November 24, 1986 (86/609/EEC) and animal care guidelines approved by the Animal Care Committee of the Institute of Molecular Genetics CAS, approval number 74/2020 and by the Animal Welfare Committee of the Charles University, approval number MSMT-26148/2022-4. We aimed to minimize the suffering and the number of animals. The mice were kept on a 12-h light/dark cycle with access to food and water ad libitum.