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Endothelial SPRY1 deficiency associates with angiogenic-metabolic reprogramming in pulmonary arterial hypertension: a multi-omics analysis of bulk and single-cell transcriptomic profiles

Crossref DOI link: https://doi.org/10.1007/s10495-025-02175-0

Published Online: 2025-09-26

Published Print: 2025-12

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Mo, Yanfei

Wang, Desheng

Deng, Zhenkun

Zhao, Pingping

Gou, Zhen

Sun, Xiaoyun

Zhang, Yunrui

Bai, Yang
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (81803530)
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Text and Data Mining valid from 2025-09-26

Version of Record valid from 2025-09-26
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Article History

Received: 6 April 2025

Accepted: 24 August 2025

First Online: 26 September 2025

Declarations

:

: The authors declare no competing interests.

: The authors declare no competing interests.

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