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Article History

Received: 21 May 2020

Accepted: 25 July 2020

First Online: 12 August 2020

Compliance with ethical standards

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: Hope Rugo received grants from Pfizer, Novartis, Eli Lilly and Company, Genentech/Roche, Macrogenics, OBI, Merck, Eisai, Immunomedics, Daiichi Sankyo, Seattle Genetics, and Odonate. She received travel support from Daiichi, Mylan, Pfizer, Merck, AstraZeneca, Novartis, Macrogenics, and is a consultant to Samsung and Puma. Sara M. Tolaney is a consultant/advisor for AstraZeneca, Eli Lilly and Company, Merck, Nektar, Novartis, Pfizer, Genentech/Roche, Immunomedics, Bristol Myers Squibb, Eisai, Nanostring, Puma, Sanofi, Celldex, Paxman, Odonate, Seattle Genetics, Silverback Therapeutics, G1 Therapeutics, AbbVie, Anthenex, OncoPep. She has received travel support from Astra Zeneca, Eli Lilly and Company, Merck, Nektar, Novartis, Pfizer, Genetech/Roche, Eisai, Immunomedics, Nanostring, Puma. Her institution received funding from Astra Zeneca, Merck, Nektar, Novartis, Pfizer, Genetech/Roche, Immunomedics, Exelixis, Eisai, Nanostring, Cyclacel, Sanofi, Odonate, Seattle Genetics. Javier Cortes is a consultant/advisor to Roche, Celgene, Cellestia, AstraZeneca, Biothera Pharmaceutical, Merus, Seattle Genetics, Daiichi Sankyo, Erytech, Athenex, Polyphor, Eli Lilly and Company, Servier, Merck Sharp & Dohme, GSK, Leuko, Bioasis, Clovis Oncology, Boehringer Ingelheim. He has received honoraria from Roche, Novartis, Celgene, Eisai, Pfizer, Samsung Bioepis, Eli Lilly and Company, Merck Sharp & Dohme, Daiichi Sankyo. His institution received research funding from Roche, Ariad Pharmaceuticals, AstraZeneca, Baxalta GMBH/Servier Affaires, Bayer Healthcare, Eisai, F.Hoffman-La Roche, Guardanth Health, Merck Sharp & Dohme, Pfizer, Piqur Therapeutics, Puma C, and Queen Mary University of London. He owns stock, patents and intellectual property in MedSIR. He received travel support from Roche, Novartis, Eisai, Pfizer, and Daiichi Sankyo. Hans Wildiers received travel support from Roche and Pfizer. His institution received consulting fees and honoraria from AbbVie, Amgen, Ariez International, AstraZeneca, Biocartes, Celldex Therapeutics, DNA Prime, Janssen-CILAG, Eli Lilly and Company, Novartis, ORION Corporation, Pfizer, The Planning Shop, PUMA Biotechnology, Roche, Sirtex, TRM Oncology, and Vifor Pharma. His institution received an unrestricted research grant from Roche. Esther Zamora received personal fees from Roche and Novartis, and non-financial support from Eli Lilly and Company, Pfyzer and Roche. Veronique Dieras has served as an advisor to Eli Lilly and Company, Roche Genetech, Pfizer, Novartis AbbVie, Daiichi Sankyo, Astra Zeneca, Merk MSD France, and Seattle Genetics. Joyce O’Shaughnessy is a consultant/advisor to AbbVie Inc., Agendia, Amgen Biotechnology, AstraZeneca, Bristol Myers Squibb, Celgene Corporation, Eisai, Genentech, Genomic Health, GRAIL, Immunomedics, Heron Therapeautics, Ipsen Biopharmaceuticals, Jounce Therapeutics, Eli Lilly and Company, Merck, Myriad, Novartis, Ondonate Therapeutics, Pfizer, Puma Biotechnology, Prime Oncology, Roche, Seattle Genetics, Syndax Pharmaceuticals, and Takeda. Denise Yardley is an advisor/consultant to Bristol Myers Squibb, Genetech, Immunomedics, Novartis, Odonate Therapeutics, R-Pharm US, Seattle Genetics. Her institution received funding from Genentech, Novartis, Odonate Therapeutics, AbbVie, Dana Farber Cancer Institute, Eli Lilly and Company, G1 Therapeutics, MacroGenics, Medivation, NSABP, Pfizer, US Oncology, Amgen, BIOMARIN, Biothera Pharmaceuticals, Clovis Pharma, Eisai, Incyte, Innocrin Pharmaceuticals, MedImmune, Merck, Merrimack Pharmaceuticals, Nektar Therapeutics, and Tesaro. Kristin M. Sheffield, Li Li, Yu-Jing Huang, Maura Dickler, Martin Frenzel, Xiaohong Ivy Li, Gebra Cuyun Carter are employees of Eli Lilly and Company and own stock in Eli Lilly and Company. Debra Patt has nothing to disclose.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

: Informed consent was obtained from all individual participants included in the study.