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Authors
Huang, Yushu
He, He
Xia, Xueqing
Jiang, Lifang
Peng, Qifeng
Du, Qingfeng
You, Yanting
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Funding
Funding for this research was provided by:
Scientific and Technological Innovation 2030-Major Project (2024ZD0523400)
Major Program of Health Science and Technology of Guangzhou (2024A031007)
Innovation Team Project of Guangdong General Colleges and Universities (2022KCXTD003)
National Science Foundation of China (82104705)
China Postdoctoral Science Foundation (2023M741603)
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Article History
Received: 15 August 2025
Accepted: 26 November 2025
First Online: 10 December 2025
Declarations
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: The clinical component of this study was approved by the Ethics Committee of Nanfang Hospital of Southern Medical University (Approval Number: NFEC-2019–064), with written informed consent obtained from all participants. Animal experiments were authorized by the Animal Ethics Committee of The Experimental Animal Ethics Committee of Guangdong Academy of Sciences (Approval Number: K2024-01–179-497) and performed in compliance with the Declaration of Helsinki and the Guide for the Care and Use of Laboratory Animals. All procedures were designed to adhere to ethical principles of animal welfare and human research protection. The data used in this study were retrieved from public databases TCGA and GEO. All datasets were obtained in accordance with the database ’s access policies, and the original studies associated with these datasets have been approved by their respective ethical committees.
: No applicable.
: The authors declare no competing interests.
