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Repeated 7-day exposure to ketamine induces anxiety-like behaviors and neuronal apoptosis in mice via DRD1-medicated inhibition of Akt/Gsk-3β phosphorylation

Crossref DOI link: https://doi.org/10.1007/s10565-026-10149-4

Published Online: 2026-01-30

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wei, Jia-yi

Lv, Peng

Zhang, Jiayu

Hou, Xi-kai

Li, Ang

Zhang, Feng-tong

Wang, Hongbo

Lu, Yan

Wu, Xu

Yao, Jun
Funding

Funding for this research was provided by:

Natural Science Foundation of Liaoning Province (2024JH2/101900012)

Natural Science Foundation of Liaoning Province (2023JH2/101600008)

National Natural Science Foundation of China (82072113)

National Natural Science Foundation of China (81971794)
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Text and Data Mining valid from 2026-01-30

Version of Record valid from 2026-02-12
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Article History

Received: 7 August 2025

Accepted: 27 January 2026

First Online: 30 January 2026

Declarations

:

: The experimental protocol was approved by the Ethics Committee of Weifang Medical College (No. SDSMU2025YX114) and the Ethics Committee for Animal Experiments of China Medical University (No. KT2022147).

: Not applicable.

: The authors declare no competing interests.

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