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A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects

Crossref DOI link: https://doi.org/10.1007/s10571-025-01587-5

Published Online: 2025-07-31

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Sharafshah, Alireza https://orcid.org/0000-0001-8048-9587
Motovali-bashi, Majid https://orcid.org/0000-0003-4380-0166
Blum, Kenneth https://orcid.org/0000-0001-6727-803X
Lewandrowski, Kai-Uwe https://orcid.org/0000-0001-7842-2914
Gold, Mark S. https://orcid.org/0000-0001-7138-8047
Keshavarz, Parvaneh https://orcid.org/0000-0002-1093-6051
Thanos, Panayotis K. https://orcid.org/0000-0002-5663-3478
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Text and Data Mining valid from 2025-07-31

Version of Record valid from 2025-07-31
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Article History

Received: 24 March 2025

Accepted: 17 June 2025

First Online: 31 July 2025

Declarations

:

: Dr. Kenneth Blum reports royalties from and discloses many pending USA and foreign patents on GARS and KB220 variants licensed to Synaptamine and Victory Nutrition International. The authors report no other conflicts of interest in this work.

: Not applicable.

: Not applicable.

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