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Article History

Received: 10 May 2022

Accepted: 12 August 2022

First Online: 22 August 2022

Declarations

:

: AK, SD, JL, JA, JB, MF, MM, GP and LA—None. JB—Consultant for Diversatek Healthcare and Merck. JC—Consultant: Alnylam, Isothrive, Medtronic, Phathom, Pfizer, Regeneron, Sanofi. PB—Co-founder Reflux Gourmet, LLC. WC—Advisory Board for Ironwood, Takeda, and Phathom Pharmaceuticals. RF—Advisor for Takeda, Daewoong, Medtronic, Phathom pharmaceuticals, Neurogastrx, GERDCare, Celexio; Speaker for Astrazeneca, Takeda, GI Supply, Eisai, Johnson & Johnson. AO—Consultant for GI Supply & Laborie Medical Inc. ES—Speaker for Abbvie, AGPharma, Alfasigma, EG Stada Group, Fresenius Kabi, Grifols, Janssen, Innovamedica, Malesci, Novartis, Pfizer, Reckitt Benckiser, Sandoz, SILA, Sofar, Takeda, Unifarco; consultant for Alfasigma, Amgen, Biogen, Bristol-Myers Squibb, Celltrion, Diadema Farmaceutici, Falk, Fresenius Kabi, Janssen, Merck & Co, Reckitt Benckiser, Regeneron, Sanofi, Shire, SILA, Sofar, Synformulas GmbH, Takeda, Unifarco; received research support from Reckitt Benckiser, SILA, Sofar, Unifarco. MV—Advisory board for Ironwood, Phatom, ISOThrive, Sanofi, Bayer pharmaceuticals and Medtronic, Diversateck healthcare, Consultation in litigation relating to acid suppressive agents. TC—Scientific Advisor and shareholder for N-Zyme Biomedical and Sofregen Medical. Receives Royalties from Plural Publishing and is a consultant for Pentax Medical and Merck.