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Article History

Received: 19 July 2019

Accepted: 13 September 2019

First Online: 10 December 2019

Compliance with ethical standards

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: T Doi has recieved consultancy from Lily, Kyowa Hakko Kirin, MSD, Daiichi Sankyo, Amgen, Sumitomo Dainippon, Taiho Pharmaceutical, Novartis, Takeda, Chugai Pharma, Abbvie and Bayer; research funding from Lily, Kyowa Hakko Kirin, MSD, Daiichi Sankyo, Sumitomo Dainippon, Taiho Pharmaceutical, Novartis, Merck Serono, Astellas Pharma, Janssen, Boehringer Ingelheim, Pfizer, Chugai Pharma, Celegene, Bristol-Myers Squibb, Abbvie, Quintiles and Eisai.N Matsubara has recieved honoraria from Janssen, Taiho Pharmaceutical and MSD; paid consultancy from Janssen, Bayer, MSD, Roche and Sanofi; speaker’s bureau from Janssen, MSD, Sanofi and AstraZeneca; research funding from Janssen, MSD, Bayer, Roche and Taiho Pharmaceutical.S Takahashi has recieved honoraria from Daiichi Sankyo, Sanofi, Eisai, Bayer, Taiho Pharmaceutical, MSD, Novartis, Chugai Pharma, AstraZeneca, Astellas Pharma, Bristol-Myers Squibb, Ono Pharmaceutical, Kyowa Hakko Kirin and Nihonkayaku; research funding from Daiichi Sankyo, Sanofi, Eisai, Bayer, Taiho Pharmaceutical, MSD, Novartis, Chugai Pharma, AstraZeneca, Bristol-Myers Squibb, Lilly and Ono Pharmaceutical; travel, accommodations, expenses from Daiichi Sankyo and Novartis.N Yamamoto has received honoraria from AstraZeneca, Pfizer, Chugai Pharma, Bristol-Myers Squibb, Ono Pharmaceutical, Lilly; paid consultancy from Eisai, Takeda, Oncothyrapy, Otsuka Pharmaceutical, Boehringer Ingelheim, ASLAN Pharmaceuticals; research funding from Chugai Pharma, Taiho Pharmaceutical, Eisai, Astellas Pharma, Novartis, Daiichi Sankyo, Lilly, Boehringer Ingelheim, Takeda, Kyowa Hakko Kirin, Bayer, Pfizer, Ono Pharmaceutical, Janssen, IQVIA, MSD, Abbvie, Bristol-Myers Squibb, Merck Serono.The remaining authors have declared no conflict of interests.

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.

: Informed consent was obtained from all individual participants included in the study.