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Article History

Received: 9 November 2020

Accepted: 16 December 2020

First Online: 1 February 2021

Compliance with ethical standards

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: Miguel Ángel Canales received speaker honoraria from Amgen, Janssen, Roche, Sandoz, Takeda; consulting fees from Celgene, Gilead, iQone, Janssen, Karyopharm, Novartis, Roche, Sandoz, Sanofi; and support for CME from Gilead, Janssen, Novartis, Roche, Sandoz, Sanofi. Paolo Corradini received honoraria as a lecturer from AbbVie, Amgen, Celgene, Gilead/Kite, Janssen, Jazz Pharmaceutics, Novartis, Roche, Sanofi, Sandoz, Takeda, and consulting fees from AbbVie, ADC Therapeutics, Amgen, Celgene, Daiichi Sankyo, Gilead, Incyte, Janssen, Kite, KiowaKirin, Novartis, Roche, Sanofi, Servier and Takeda. Francesco Zaja received honoraria from Novartis, Amgen, Janssen, Takeda, Celgene, Abbvie, Roche, Mundipharma and Grifols. Juan-Manuel Sancho received advisory council or committee fees from Roche, Gilead, Janssen, Celgene, Incyte, Celltrion, Novartis, and honoraria as a speaker from Roche, Gilead, Janssen, Celgene, Incyte, Takeda, Novartis, Sanofi and Servier. Anne-Marie Quinson, Valérie Belsack and Daniela Maier are employees of Boehringer Ingelheim. Carmelo Carlo-Stella received honoraria from Bristol-Myers Squibb, Merck Sharp & Dohme, Servier, Amgen, Janssen Oncology, Sanofi, ADC Therapeutics, Novartis, and AstraZeneca; provided consultancy to Boehringer Ingelheim, Genenta Science, Sanofi, ADC Therapeutics, and received research funding from Rhizen Pharmaceuticals. Monica Balzarotti, Massimo Magagnoli and Carlos Grande report no conflict of interest. 

: All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. 

: Informed consent was obtained from all individual participants included in the study.