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Authors
Darbani, Behrooz https://orcid.org/0000-0003-0289-6392
Brodersen, Thorsten https://orcid.org/0000-0003-4431-9972
Liljensøe, Anette https://orcid.org/0000-0003-3937-0095
Sørensen, Signe Bek
Olsson-Svendsen, Josephine Bjergbæk https://orcid.org/0000-0002-7195-3074
Buil, Alfonso
Kamal, Ahmed
Schork, Andrew J.
Poulsen, Anja https://orcid.org/0000-0002-0314-3467
Kjerulff, Bertram Dalskov https://orcid.org/0000-0001-9953-9521
Aagaard, Bitten https://orcid.org/0000-0001-8306-1332
Lund, Britta Ørnfelt
Rittig, Charlotte Siggaard
Mikkelsen, Christina https://orcid.org/0000-0002-2945-6197
Larsen, Daniel Millencourt
Westergaard, David https://orcid.org/0000-0003-0128-8432
Rudbeck-Resdal, Ditte
Mikkelsen, Dorte Helenius
Randers, Else
Schiødt, Frank Vinholt
Hoffmann, Hans Jürgen https://orcid.org/0000-0002-6743-7931
Jørgensen, Isabella Friis
Brandslund, Ivan https://orcid.org/0000-0002-4203-5442
Brodersen, Jacob Broder https://orcid.org/0000-0003-2530-7554
von Stemann, Jakob Hjorth
Bay, Jakob Thaning https://orcid.org/0000-0003-1159-4003
Nissen, Janna https://orcid.org/0000-0002-8891-8451
Sørensen, Jeanette
Boldsen, Jens Kjærgaard https://orcid.org/0000-0002-8139-1642
Dowsett, Joseph https://orcid.org/0000-0001-5381-2633
Gladov, Josephine https://orcid.org/0000-0001-9233-3117
Banasik, Karina
Kaspersen, Kathrine Agergård https://orcid.org/0000-0002-7973-3623
Carlsen, Katrine https://orcid.org/0000-0002-3175-3529
Dinh, Khoa Manh https://orcid.org/0000-0003-1881-5673
Kellermann, Lauge
Christoffersen, Lea Arregui Nordahl https://orcid.org/0000-0002-5816-6324
Quinn, Liam James Elgaard
Thørner, Lise Wegner https://orcid.org/0000-0003-4391-4956
Larsen, Lone https://orcid.org/0000-0003-4067-2381
Aamann, Luise https://orcid.org/0000-0003-0046-887X
Andersen, Malene Rohr
Didriksen, Maria https://orcid.org/0000-0002-4856-496X
Alexandraki, Maria Joanna
Thomsen, Marianne Kragh https://orcid.org/0000-0002-3645-6689
Julsgaard, Mette https://orcid.org/0000-0003-3070-8950
Nyegaard, Mette https://orcid.org/0000-0003-4973-8543
Schwinn, Michael
Topholm-Bruun, Mie
Leite, Mikael Njai https://orcid.org/0009-0007-0158-3016
Halling, Morten Lee https://orcid.org/0000-0003-3610-6563
Pedersen, Natalia
Bonderup, Ole K. https://orcid.org/0000-0003-3199-3474
Rohde, Palle Duun
Ovesen, Pernille Dige https://orcid.org/0000-0001-5513-2914
Dessau, Ram Benny https://orcid.org/0000-0002-1497-6309
Saboori, Sanaz
Holm-Christensen, Sofie
Bank, Steffen https://orcid.org/0009-0003-5929-6168
Mikkelsen, Susan
Hansen, Thomas Folkmann https://orcid.org/0000-0001-6703-7762
Werge, Thomas
Qvist, Niels
Sørensen, Erik https://orcid.org/0000-0002-5002-9077
Burisch, Johan https://orcid.org/0000-0002-3312-5139
Hetland, Merete Lund https://orcid.org/0000-0003-4229-6818
Glintborg, Bente https://orcid.org/0000-0002-8931-8482
Erikstrup, Christian https://orcid.org/0000-0001-6551-6647
Brunak, Søren https://orcid.org/0000-0003-0316-5866
Ullum, Henrik
Ostrowski, Sisse Rye https://orcid.org/0000-0001-5288-3851
Pedersen, Ole Birger Vesterager https://orcid.org/0000-0003-2312-5976
Andersen, Vibeke https://orcid.org/0000-0002-0127-2863
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Funding
Funding for this research was provided by:
Novo Nordisk Fonden (NNF15OC0016932, NNF23OC0082015, NNF17OC0027864, NNF17OC0027594)
Knud og Edith Eriksens Mindefond
Gigtforeningen (A2037, A3570)
Bio- and Genome Bank Denmark
Administrative Regions (02/2611)
Danish Council for Independent Research (09–069412)
Infrastructure of Bio- and Genome Bank Denmark
Department of Clinical Immunology, Rigshospitalet, Copenhagen University Hospital
Rigshospitalet Research Council
Danish Rheumatism Association
Danish Regions
University of Southern Denmark
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Article History
Received: 19 December 2024
Accepted: 24 April 2025
First Online: 9 June 2025
Declarations
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: All personal fees and grants were received outside this work. Anja Poulsen reports research grants and personal fees from Janssen, Takeda, and MSD, personal fees from Bristol Myers Squibb, national coordinator of studies from Agomab, Boehringer Ingelheim and Bristol Myers. Bente Glintborg has received research grants (paid to institution) from AbbVie, Pfizer, BMS, Sandoz. Bente Glintborg chairs the DANBIO steering committee. Jacob Broder Brodersen has received consultation fee from Jansen-Cilag. Johan Burisch reports grants and personal fees from AbbVie, Janssen-Cilag, Takeda, Tillots Pharma, Bristol Myers Squibb, and MSD, personal fees from Celgene, Pfizer, Samsung Bioepis, Pharmacosmos, Ferring, Galapagos, and Eli Lilly, and grants from Novo Nordisk Foundation. Mette Julsgaard has received research grants from Takeda and the Novo Nordisk Foundation (grant no. NNF23OC0081717), has been on the advisory board of PharmaCosmos, has received consultation fee from Ferring and Takeda, and has received speaker’s fees from Tillotts Pharma, MSD, Ferring, and Takeda. Vibeke A ndersen has served as advisory board member for MSD (Merck). Søren Brunak has ownerships in Intomics A/S, Hoba Therapeutics Aps, Novo Nordisk A/S, Lundbeck A/S, ALK abello A/S, Eli Lilly and Co and managing board memberships in Proscion A/S and Intomics A/S. Thorsten Brodersen’s spouse currently holds incentive stock options in LEO Pharma A/S. All other authors declare no conflict of interest.
: CHB-CID:IBD studies will be conducted in accordance with the Declaration of Helsinki and has been approved by the National and the Capital, Central Denmark, and South Denmark Regional Committees on Health Research Ethics (NVK-1700407, H-18064178, M20100153, S-20120113, and S-20160124), as well as the Data Protection Agency of Capital (P-2019–99 and P-2022–876), Central (RM: J. 2010–41-4719) and Southern (RSD: 2008–58-035) Denmark. All individuals in CHB have been informed about their inclusion into the biobank and the use of their data for research.
: ChatGPT () assisted copy editing was used and authors reviewed and revised the final version, taking full responsibility for the content of the publication.
