Du, Mike
Prats-Uribe, Albert
Mercadé-Besora, Núria
Lopez-Guell, Kim
Guo, Yuchen
Alcalde-Herraiz, Marta
Chen, Xihang
Delmestri, Antonella
Man, Wai Yi
Duarte-Salles, Talita
Palomar, Anna
Giuliodori, Agustina
Brađašević, Emanuel
Jezidžić, Antea
Bräuner, Elvira
Bruun, Susanne
Verhamme, Katia
Mosseveld, Mees
Brash, James T.
Vojinovic, Dina
Kaczmarczyk, Isabella
Mendez, Akram
Rijnbeek, Peter
Prieto-Alhambra, Daniel
Burn, Edward
Català, Martí https://orcid.org/0000-0003-3308-9905
Article History
Received: 11 September 2025
Accepted: 16 December 2025
First Online: 3 April 2026
Declarations
:
: DPA’s research group from the University of Oxford has received research grants from the Innovative Medicines Initiative, from Gilead Science, from Theramex, and from UCB Biopharma, none of which are related to this manuscript. The department of Medical Informatics receives/received in the past 3 years unconditional research grants from UCB, Chiesi, Amgen and Johnson and Johnson. JB, DV, IK and AM are employees of IQVIA. TDS, AP and AG receives/received research grants from Innovative Medicines Initiative and European Medicines Agency, none of which relate the content of this manuscript.
: For CPRD, the study protocol (24_004487) was approved by the Research Data Governance Process. The use of IPCI data was approved by the Erasmus MC (protocol: 10/2022 & 11/2022). Research Ethics Committee of the Croatian National Public Health Information System (NAJS) (protocol:117-15-24-16). For SIDIAP, ethics approval was received by the Clinical Research Ethics Committee of the IDIAPJGol (project code: 24/283-EOm). For Danish Data Health Registries (DK-DHR), ethics has an umbrella approval for DARWIN studies. IQVIA databases are exempt from specific ethics approval submissions.