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Article History

Received: 19 April 2025

Accepted: 13 June 2025

First Online: 12 July 2025

Declarations

:

: The authors declare no conflict of interests.

: All the animal experiments in this study were conducted based on the regulations of Iran University of Medical Sciences Ethical Committee with code: IR.IUMS.REC.1401.493.

: What is the current knowledge? - Chitosan/alginate (1:2) hydrogel had better wound healing than the gauze-treated wounds. - Quercetin shows anti-inflammatory and antioxidant and wound healing properties. What is new here? An investigation was conducted using a chitosan/alginate hydrogel (2:1) dressing containing quercetin to explore the combined synergic impact on skin regeneration in diabetic rat model.

: Supplementary Data 1. Chitosan/ Alginate/ Quercetin hydrogel.

: Supplementary Data 2. Diabetic Wistar rat models treated with chitosan/ alginate dressing with or without quercetin at Days 1, 7 and 14.