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Authors
Wu, Bibo
Zhao, Shasha
Zhang, Jing
Liu, Yao
Bai, Jie
Wang, Gang
Wang, Yu
Jiang, Han
Hu, Yinxiang
OuYang, Weiwei
Lu, Bing
Su, Shengfa
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (81960548)
Guizhou Provincial Natural Science Foundation, China (ZK (2022) key040)
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Article History
Received: 2 February 2024
Revised: 12 May 2024
Accepted: 15 May 2024
First Online: 21 May 2024
Declarations
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: The authors declare no competing interests.
: There are some limitations to this study. First of all, in most animal models established by researchers to explore the mechanism of RIHD, the irradiation method is to receive the same dose of whole-heart irradiation, which does not involve in vivo tumors. However, in clinical practice, the radiation dose received by different areas in the heart of patients with thoracic tumors varies greatly. A single dose of 20 Gy to the heart is not directly related to exposure to radiation therapy. Secondly, only male mice were studied, and the effects on female mice may be different. Thirdly, each of the analyses contained a very small number of mice.
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