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Antioxidative and anti-inflammatory effects of Carvacrol against polycystic ovary syndrome associated complications using high fat diet and Letrozole challenged rat model: a multidisciplinary study cascading in vivo, in vitro, in silico and network pharmacology approaches

Crossref DOI link: https://doi.org/10.1007/s10787-025-01809-8

Published Online: 2025-06-20

Published Print: 2025-08

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Siddiqua, Arfah

Malik, Abdul https://orcid.org/0000-0002-9315-0301
Iqbal, Urooj https://orcid.org/0009-0005-7536-0064
Sial, Nabeela Tabassum

Mehmood, Malik Hassan

Rehman, Muhammad Fayyaz ur
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Article History

Received: 2 March 2025

Accepted: 27 May 2025

First Online: 20 June 2025

Declarations

:

: The authors declare no conflict of interest.

: The current study offers a path ahead to investigate the detailed mechanisms of Carvacrol for the management of polycystic ovarian syndrome, using a targeted approach.

: The research methodologies were approved through the University of Sargodha’s Biosafety and Ethical Review Committee for Animal Use (Approval No. ERB/SS/070424).

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