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Kaempferol prevents Nrf2 from ubiquitin-mediated proteolysis to mitigate both NLRP3 inflammation and oxidative stress: implications for alleviating DSS-induced colitis in mice

Crossref DOI link: https://doi.org/10.1007/s10787-025-01966-w

Published Online: 2025-10-04

Published Print: 2025-11

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Hua, Wentian

Li, Minrui

Yan, Ziwei

Wang, Yingchao

Zhou, Xiang

Fu, Zhiwen

Wang, Yi

Zhang, Shujing

Qian, Jing https://orcid.org/0000-0002-1642-9202
Funding

Funding for this research was provided by:

Key Technologies Research and Development Program (2023YFC3502801)

National Natural Science Foundation of China (82304755)

Medical Science and Technology Project of Zhejiang Province (2024ZL343)
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Article History

Received: 9 July 2025

Accepted: 7 September 2025

First Online: 4 October 2025

Declarations

:

: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

: All animal experiments were approved by the review committee of Zhejiang University with the ethics approval number ZJU20240686 and were conducted in accordance with principles for laboratory.

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