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Authors
Perazzio, Ana Clara
Lopes, João Pedro V.
Becker, Gabriela
Brum, Evelyne Silva
Oliveira, Sara Marchesan https://orcid.org/0000-0003-2960-5284
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Funding
Funding for this research was provided by:
Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (21/2551–0001966-2)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (process #88881.844988/2023–01; Grant #1333/2023)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Grant #88887.015792/2024-00)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (#309404/2023–1)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (#152071/2024-5)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (#150611/2022-6)
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Article History
Received: 22 August 2025
Accepted: 16 November 2025
First Online: 8 December 2025
Declarations
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: The authors declare that there are no conflicts of interest. All authors reviewed the manuscript and agreed to submit and publish data in Inflammopharmacology .
: Animal care and experimental protocols were approved by the Institutional Animal Care and Use Committee of the Federal University of Santa Maria (protocol #9104130923), in accordance with the ethical guidelines for studying experimental pain in conscious animals (Zimmermann ) and national legislation (Guidelines of the Brazilian Council of Animal Experimentation Control: CONCEA).
