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Authors
Unal, Adem https://orcid.org/0000-0001-6251-200X
Bozkurt Oflaz, Ayse https://orcid.org/0000-0001-5894-0220
Cetin, Nihal https://orcid.org/0000-0003-3233-8009
Yayla, Muhammed https://orcid.org/0000-0002-0659-3084
Menevse, Esma https://orcid.org/0000-0002-5477-5667
Celik, Zeliha Esin https://orcid.org/0000-0002-3220-7845
Tugay, Osman https://orcid.org/0000-0003-3980-7648
Bozkurt, Banu https://orcid.org/0000-0002-9847-3521
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Funding
Funding for this research was provided by:
Selçuk University Research Foundation (25122008)
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Article History
Received: 21 December 2025
Accepted: 21 February 2026
First Online: 3 March 2026
Declarations
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: The authors declare no competing interests.
: This study was approved by the Selcuk University Faculty of Medicine Experimental and Observational Research Ethics Committee (Ethics Committee Approval No: 2024/63). All experimental procedures were carried out in accordance with national legislation on animal welfare and the relevant directives of the International Committee on Animal Experiments Ethics (CIOMS) and the European Convention. All necessary precautions were taken to ensure that the animals did not feel pain, stress, or discomfort during the study; all procedures were carried out under veterinary supervision and in accordance with the principle of minimized invasiveness. This study was planned and implemented in accordance with the 3R (Replace, Reduce, Refine) principles within the framework of ethical rules.
