Howard, Andrea L. http://orcid.org/0000-0002-9843-9577
Kennedy, Traci M.
Macdonald, Erin P.
Mitchell, John T.
Sibley, Margaret H.
Roy, Arunima
Arnold, L. Eugene
Epstein, Jeffery N.
Hinshaw, Stephen P.
Hoza, Betsy
Stehli, Annamarie
Swanson, James M.
Molina, Brooke S. G.
Funding for this research was provided by:
National Institute of Mental Health (U01MH50461, N01MH12009, U01MH50477, N01MH12012, U01MH50440, N01MH12011, U01 MH50467, N01 MH12007, U01 MH50453, N01MH 12004, N01MH 12010, N01MH12008)
National Institute on Drug Abuse (N01DA-8-5550, N01DA-8-5554, N01DA-8-5551, N01DA-8- 5552, N01DA-8-5549, N01DA-8-5553, N01DA-8-5548, R01DA039881)
Article History
First Online: 5 July 2019
Compliance with Ethical Standards
:
: J.T.M. consulted with Avanir. L.E.A. received research funding from Forest, Lilly, Noven, Roche/Genentech, Shire, Supernus, and YoungLiving (as well as NIH and Autism Speaks), and consulted with Pfizer, Tris Pharma, and Waypoint, and been on advisory boards for Arbor, Ironshore, Otsuka, Pfizer, Roche/Genentech, Seaside Therapeutics, and Shire. J.M.S. acknowledges research support, advisory board/ speaker’s bureau and/or consulting for Alza, Richwood, Shire, Celgene, Novartis, Celltech, Gliatech, Cephalon, Watson, CIBA, UCB, Janssen, McNeil, Noven, NLS, Medice, and Lilly. J.N.E. received consulting fees from American Academy of Pediatrics and American Board of Pediatrics, received royalties from Multi-Health Systems, Optimal Medicine, and IXICO, and received research support from Akili Interactive Labs. A.R. was supported by an Alexander von Humboldt fellowship in 2017-2018. The other remaining authors have declared that they have no competing or potential conflicts of interest.
: The Multimodal Treatment Study of Children with ADHD (MTA) was a National Institute of Mental Health (NIMH) cooperative agreement randomized clinical trial with the observational phase funded by NIMH and the National Institute on Drug Abuse (NIDA) to the following: University of California–Berkeley*: U01MH50461, N01MH12009, N01DA-8-5550; Duke University*: U01MH50477, N01MH12012, N01DA-8-5554; University of California, Irvine*: U01MH50440, N01MH12011, N01DA-8-5551; Research Foundation for Mental Hygiene (New York State Psychiatric Institute*/Columbia University): U01 MH50454, N01 MH12007, N01DA-8- 5552; Long Island–Jewish Medical Center*: U01 MH50453; New York University: N01MH 12,004, N01DA-8-5549; University of Pittsburgh*: U01 MH50467, N01MH 12,010, N01DA-8-5553; McGill University N01MH12008, N01DA-8-5548. A data analysis grant awarded to the University of Pittsburgh (DA039881) followed. IRB ethics approvals for primary data collection at the RCT and observational phases were obtained from all above sites marked with an asterisk* as well as at Mount Sinai Medical Center and Montréal Children’s Hospital. The opinions and assertions contained in this report are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of Health and Human Services, the National Institutes of Health or the National Institute of Mental Health.
: Informed consent (parental permission and child assent) was obtained from all participating families prior to completing study procedures. Once they reached age 18, participants provided their own informed consent. All participating study sites (see Author note for a detailed list) obtained IRB ethics approval. Secondary data analysis procedures were approved by the Carleton University Research Ethics Board.