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Authors
Xu, Qianhua
Ding, Haitian
Liu, Yingchun
Han, Dan
Xia, Xun
Li, Yuqian
Sha, Xuan
Li, Guotong
Ni, Xiaoqing
Li, Kuokuo
Hua, Rong
He, Xiaojin
Wu, Huan https://orcid.org/0000-0002-0009-3839
Cao, Yunxia https://orcid.org/0000-0002-8715-0874
Xu, Yuping https://orcid.org/0000-0002-2034-1086
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (rant No. 82471648)
National Natural Science Foundation of China (82201803)
National Natural Science Foundation of China (82271639)
National Natural Science Foundation of China (82371622)
Clinical Translational Medicine Research Program (202204295107020037)
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Article History
Received: 11 April 2025
Accepted: 29 August 2025
First Online: 11 September 2025
Declarations
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: This study was conducted in accordance with the ethical standards of the Declaration of Helsinki and ICMJE recommendations, with protocol approval granted by the Ethics Committee of the First Affiliated Hospital of Anhui Medical University (P2020-12–36). All participants provided written informed consent after receiving detailed explanations regarding study objectives, potential risks/benefits, and data usage protocols. Personal identifiers were removed using pseudonymization prior to analysis, with genetic and clinical data stored in secure encrypted databases compliant. No human tissue/organ samples were utilized in this genetic analysis study.
: All authors consent to the publication of this work and authorize granting this license.
: The authors declare no competing interests.
