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Early cardioprotective effects of SGLT2i on hypertensive cardiac remodeling via STIM1/Orai1-dependent calcium signaling: beyond blood pressure control

Crossref DOI link: https://doi.org/10.1007/s10863-025-10067-w

Published Online: 2025-07-28

Published Print: 2025-10

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wu, Jian

Jia, Zhuoran

Wu, Xiaohe

Xue, Yangcheng

Zheng, Peiyang

Wang, Huimin

Zhao, Ren
Funding

Funding for this research was provided by:

National Natural Science Foundation of China (82371949)

Natural Science Foundation of Anhui Province (202304295107020029)
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Text and Data Mining valid from 2025-07-28

Version of Record valid from 2025-07-28
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Article History

Received: 6 May 2025

Accepted: 25 June 2025

First Online: 28 July 2025

Declarations

:

: The animal protocol of this study was approved by the Ethics Committee of Anhui Medical University (Anhui Medical Ethics Approval No. LLSC20190530), and all experimental methods and procedures were carried out in accordance with the National Institutes of Health guidelines (Publication No. 8523) to comply with all relevant ethical regulations for animal testing and research.

: Not applicable.

: The authors declare no competing interests.

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