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Opioid administration guided by Surgical Pleth Index in patients with a combination of general and regional anaesthesia during trauma and orthopaedic surgery: a double-blind, randomised controlled trial

Crossref DOI link: https://doi.org/10.1007/s10877-025-01363-2

Published Online: 2025-10-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Koschmieder, Kim C.

Pinnschmidt, Hans O.

Borst, Lea-Sophie

Greiwe, Gillis

Kainz, Elena

Fischer, Marlene

Nitzschke, Rainer
Funding

Funding for this research was provided by:

Universitätsklinikum Hamburg-Eppendorf (UKE)
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Text and Data Mining valid from 2025-10-03

Version of Record valid from 2025-10-03
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Article History

Received: 19 June 2025

Accepted: 21 September 2025

First Online: 3 October 2025

Declarations

:

: The authors declare no competing interests.

: This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the regional ethics review board of the Medical Council of Hamburg, Germany (August 18, 2023, reference number 2023-101127-BO-ff).

: Informed consent was obtained from all individual participants included in the study.

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