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Article History

Received: 11 November 2024

Accepted: 22 March 2025

First Online: 1 April 2025

Declarations

:

: The authors declare no competing interests.

: The experimental protocol of our study was performed in accordance with the Guide for the Care and Use of Laboratory Animals and approved by Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences (SDTHEC2023011024). The protocol of this research has been approved by the Ethics Committee of Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences (SDTHEC2019-155–05). The research complied with the Declaration of Helsinki. All patients have signed written informed consent.

: None.